ANTI-SEROTONIN TRANSPORTER

Analysis Note

ControlWestern Blot : Human lung lysate.

Application

Research Sub CategoryIon Channels & Transporters

Research CategoryNeuroscience

This Anti-Serotonin Transporter Antibody is validated for use in WB for the detection of Serotonin Transporter.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Immunogen

Epitope: Center region

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human serotonin transporter.

Linkage

Replaces: AB1594P

Physical form

Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Antigen Affinity Purified

Quality

Western Blot Analysis: 1:1000 dilution of this antibody detected serotonin transporter on human lung lysate.

Specificity

The antibody reacts with the 70 kDa serotonin transporter protein.

Other species have not been tested.

Storage and Stability

Store at 2-8°C for 1 year from date of receipt.

Target description

70 kDa